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Figure 2 – Dose surface maps of the rectum during prostate radiotherapy, generated from the original kilovoltage planning scan (left) and megavoltage on-treatment image (right). Differences in high- (red) and intermediate- (yellow) dose regions can be attributed to anatomical positional variation and have previously been linked to toxicity effects. The additional information provided by this novel on-treatment imaging and analysis technique will allow improved correlation between accumulated dose and patient reported side-effects. Images courtesy of Dr Simon Thomas, Head of Medical Physics and Clinical Engineering, Addenbrooke’s Hospital, Cambridge University Hospitals.

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